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Crystal structure of the MSL1-MSL2 complex

Source organism: Homo sapiens
Biochemical function: ubiquitin protein ligase activity
Biological process: not assigned
Cellular component: MSL complex

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF16685
Domain description: zinc RING finger of MSL2
Occurring in:
  1. E3 ubiquitin-protein ligase MSL2
The deposited structure of PDB entry 4b7y contains 2 copies of Pfam domain PF16685 (zinc RING finger of MSL2) in E3 ubiquitin-protein ligase MSL2. Showing 1 copy in chain C.

PF16801
Domain description: Dimerisation domain of Male-specific-Lethal 1
Occurring in:
  1. Male-specific lethal 1 homolog
The deposited structure of PDB entry 4b7y contains 2 copies of Pfam domain PF16801 (Dimerisation domain of Male-specific-Lethal 1) in Male-specific lethal 1 homolog. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR032043
Domain description: E3 ubiquitin-protein ligase Msl2, zinc RING finger
Occurring in:
  1. E3 ubiquitin-protein ligase MSL2
IPR001841
Domain description: Zinc finger, RING-type
Occurring in:
  1. E3 ubiquitin-protein ligase MSL2
IPR037922
Domain description: E3 ubiquitin-protein ligase MSL2
Occurring in:
  1. E3 ubiquitin-protein ligase MSL2
IPR013083
Domain description: Zinc finger, RING/FYVE/PHD-type
Occurring in:
  1. E3 ubiquitin-protein ligase MSL2
IPR031840
Domain description: Protein male-specific lethal-1, dimerisation domain
Occurring in:
  1. Male-specific lethal 1 homolog
IPR026711
Domain description: Protein male-specific lethal-1
Occurring in:
  1. Male-specific lethal 1 homolog

Structure domain

CATH CATH domain
3.30.40.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Herpes Virus-1
Homology: Zinc/RING finger domain, C3HC4 (zinc finger)
Occurring in:
  1. E3 ubiquitin-protein ligase MSL2
The deposited structure of PDB entry 4b7y contains 2 copies of CATH domain 3.30.40.10 (Herpes Virus-1) in E3 ubiquitin-protein ligase MSL2. Showing 1 copy in chain C.

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