PDBe 4b1b

X-ray diffraction
2.9Å resolution

Crystal structure of Plasmodium falciparum oxidised Thioredoxin Reductase at 2.9 angstrom

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 542 amino acids
Theoretical weight: 59.78 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q25861 (Residues: 2-541; Coverage: 100%)
Gene names: GR, TR
Sequence domains:
Structure domains: FAD/NAD(P)-binding domain

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 63.187Å b: 109.242Å c: 182.414Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.266 0.265 0.288
Expression system: Escherichia coli BL21(DE3)