4avp

X-ray diffraction
1.82Å resolution

Crystal structure of the DNA-binding domain of human ETV1.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ETS translocation variant 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 106 amino acids
Theoretical weight: 12.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P50549 (Residues: 326-429; Coverage: 22%)
Gene names: ER81, ETV1
Sequence domains: Ets-domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P1
Unit cell:
a: 33.317Å b: 45.607Å c: 55.406Å
α: 77.89° β: 84.8° γ: 90.02°
R-values:
R R work R free
0.223 0.221 0.258
Expression system: Escherichia coli BL21(DE3)