› › Structure analysis

Structure of the FimH lectin domain in the trigonal space group, in complex with a methanol triazol ethyl phenyl alpha-D-mannoside at 2.1 A resolution

X-ray diffraction
2.105Å resolution
PDB entry 4avj coloured by chain, front view.
PDB entry 4avj coloured by chain, side view.
PDB entry 4avj coloured by chain, top view.
Source organism: Escherichia coli UTI89
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Type 1 fimbrin D-mannose specific adhesin
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 7740.89 Å2
Buried surface area: 376.95 Å2
Dissociation area: 52.62 Å2
Dissociation energy (ΔGdiss): 7.77 kcal/mol
Dissociation entropy (TΔSdiss): -0.13 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-140004
Assembly 2
Download    3D Visualisation
Assembly Name: Type 1 fimbrin D-mannose specific adhesin
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 7525.86 Å2
Buried surface area: 104.86 Å2
Dissociation area: 52.43 Å2
Dissociation energy (ΔGdiss): 7.78 kcal/mol
Dissociation entropy (TΔSdiss): -0.13 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-140004

Macromolecules

Type 1 fimbrin D-mannose specific adhesin
Chains: A, B
Length: 158 amino acids
Theoretical weight: 16.92 KDa
Source organism: Escherichia coli UTI89
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08191 (Residues: 22-179; Coverage: 57%)
Gene names: JW4283, b4320, fimH
Pfam: FimH, mannose binding
InterPro:
CATH: Fimbrial-type adhesion domain
Type 1 fimbrin D-mannose specific adhesin in PDB entry 4avj, assembly 1, front view.
Type 1 fimbrin D-mannose specific adhesin in PDB entry 4avj, assembly 1, side view.
Type 1 fimbrin D-mannose specific adhesin in PDB entry 4avj, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links