4at8

X-ray diffraction
2.69Å resolution

Crystal structure of the NF90-NF45 dimerisation domain complex with ATP

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-190023 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin enhancer-binding factor 2 Chains: A, C
Molecule details ›
Chains: A, C
Length: 364 amino acids
Theoretical weight: 40.36 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9CXY6 (Residues: 29-390; Coverage: 93%)
Gene names: Ilf2, Nf45
Sequence domains:
Structure domains:
Interleukin enhancer-binding factor 3 Chains: B, D
Molecule details ›
Chains: B, D
Length: 383 amino acids
Theoretical weight: 42.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9Z1X4 (Residues: 1-381; Coverage: 42%)
Gene name: Ilf3
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21
Unit cell:
a: 70.871Å b: 84.128Å c: 159.597Å
α: 90° β: 93.34° γ: 90°
R-values:
R R work R free
0.241 0.24 0.266
Expression system: Escherichia coli BL21