PDBe 4asz

X-ray diffraction
1.7Å resolution

Crystal structure of apo TrkB kinase domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BDNF/NT-3 growth factors receptor Chain: A
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 34.35 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q16620 (Residues: 527-822; Coverage: 37%)
Gene names: NTRK2, TRKB
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21212
Unit cell:
a: 86.993Å b: 96.777Å c: 46.378Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.178 0.203
Expression system: Spodoptera frugiperda