4arr

X-ray diffraction
3Å resolution

Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C

Released:
Primary publication:
Liesegang-like patterns of Toll crystals grown in gel.
J Appl Crystallogr 46 337-345 (2013)
PMID: 23596340

Function and Biology Details

Reaction catalysed:
(1a) NAD(+) = cyclic ADP-ribose + nicotinamide
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LRRNT domain-containing protein; Protein toll Chains: A, B
Molecule details ›
Chains: A, B
Length: 279 amino acids
Theoretical weight: 31.96 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q4G1L2 (Residues: 136-201; Coverage: 26%)
  • Canonical: P08953 (Residues: 28-233; Coverage: 19%)
Gene names: CG5490, Tl, VLRB
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P43212
Unit cell:
a: 87.643Å b: 87.643Å c: 220.741Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.224 0.254
Expression system: Spodoptera frugiperda