PDBe 4apt

X-ray diffraction
2.5Å resolution

The structure of the AXH domain of ataxin-1.

Released:

Function and Biology Details

Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ataxin-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 126 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54253 (Residues: 566-688; Coverage: 15%)
Gene names: ATX1, ATXN1, SCA1
Sequence domains: Ataxin-1 and HBP1 module (AXH)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 41.47Å b: 80.83Å c: 139.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.236 0.288
Expression system: Escherichia coli BL21(DE3)