4aor

X-ray diffraction
1.7Å resolution

Cationic trypsin in complex with the Spinacia oleracea trypsin inhibitor III (SOTI-III)

Released:
Source organisms:
Primary publication:
Structural characterization of Spinacia oleracea trypsin inhibitor III (SOTI-III).
Acta Crystallogr. D Biol. Crystallogr. 69 114-20 (2013)
PMID: 23275169

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cationic trypsin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Trypsin inhibitor 3 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 37 amino acids
Theoretical weight: 3.84 KDa
Source organism: Spinacia oleracea
Expression system: Not provided
UniProt:
  • Canonical: P84781 (Residues: 1-37; Coverage: 100%)
Sequence domains: Trypsin inhibitors 1,2 and 3

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 49.35Å b: 66.82Å c: 108.89Å
α: 90° β: 90.17° γ: 90°
R-values:
R R work R free
0.181 0.179 0.221
Expression system: Not provided