4aj0

X-ray diffraction
1.7Å resolution

Crystallographic structure of an amyloidogenic variant, 3rCW, of the germinal line lambda 3

Released:
Source organism: Homo sapiens
Entry authors: Villalba MI, Luna OD, Rudino-Pinera E, Sanchez R, Sanchez-Lopez R, Rojas-Trejo S, Olamendi-Portugal T, Fernandez-Velasco DA, Becerril B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GERMINAL LINE LAMBDA 3 3RCW VARIANT Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 107 amino acids
Theoretical weight: 11.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P31
Unit cell:
a: 41.807Å b: 41.807Å c: 171.035Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.174 0.212
Expression system: Escherichia coli BL21(DE3)