X-ray diffraction
1.75Å resolution

Crystal Structure of Fucose binding lectin from Aspergillus Fumigatus (AFL) in complex with BGA Oligosaccharide.

Source organism: Aspergillus fumigatus
Entry authors: Houser J, Komarek J, Kostlanova N, Lahmann M, Cioci G, Varrot A, Imberty A, Wimmerova M

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Fucose-specific lectin Chains: A, B
Molecule details ›
Chains: A, B
Length: 315 amino acids
Theoretical weight: 34.64 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli BL21
  • Canonical: Q4WW81 (Residues: 1-315; Coverage: 100%)
Gene names: AFUA_5G14740, fleA
Sequence domains: Fungal fucose-specific lectin
Structure domains: Fucose-specific lectin

Ligands and Environments

Carbohydrate polymer : NEW Components: FUC, GAL, A2G
2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P1
Unit cell:
a: 46.42Å b: 47.44Å c: 80.086Å
α: 103.61° β: 91.96° γ: 113.08°
R R work R free
0.17 0.168 0.211
Expression system: Escherichia coli BL21