X-ray diffraction
2.3Å resolution

Leishmania TDR1 - a unique trimeric glutathione transferase


Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Thiol-dependent reductase 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 471 amino acids
Theoretical weight: 53.2 KDa
Source organism: Leishmania infantum
Expression system: Escherichia coli B
  • Canonical: A4I8P2 (Residues: 1-450; Coverage: 100%)
Gene names: LINJ_33_0260, TDR1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: C2
Unit cell:
a: 197.477Å b: 58.396Å c: 160.385Å
α: 90° β: 111.81° γ: 90°
R R work R free
0.152 0.149 0.208
Expression system: Escherichia coli B