X-ray diffraction
1.94Å resolution

Dimeric alpha-cobratoxin X-ray structure: Localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors


Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-cobratoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 71 amino acids
Theoretical weight: 7.84 KDa
Source organism: Naja kaouthia
  • Canonical: P01391 (Residues: 1-71; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P3121
Unit cell:
a: 86Å b: 86Å c: 37.12Å
α: 90° β: 90° γ: 120°
R R work R free
0.22 0.219 0.251