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Selenomethionine derivative of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron

Source organism: Bacteroides thetaiotaomicron VPI-5482
Biochemical function: hydrolase activity, acting on glycosyl bonds
Biological process: not assigned
Cellular component: membrane

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EC 3.2.1.130: Glycoprotein endo-alpha-1,2-mannosidase

Reaction catalysed:
GlcMan(9)GlcNAc(2)-[protein] + H(2)O = Man(8)GlcNAc(2)-[protein] (isomer 8A(1,2,3)B(1,2)) + alpha-D-glucosyl-(1->3)-alpha-D-mannopyranose
Systematic name:
Glycoprotein glucosylmannohydrolase (configuration-retaining)
Alternative Name(s):
  • Endo-alpha-D-mannosidase
  • Endo-alpha-mannosidase
  • Endomannosidase
  • Glucosyl mannosidase
  • Glucosylmannosidase
  • Glycoprotein glucosylmannohydrolase
  • MANEA (gene name)

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF16317
Domain description: Glycosyl hydrolase family 99
Occurring in:
  1. Endo-alpha-mannosidase
The deposited structure of PDB entry 4acy contains 2 copies of Pfam domain PF16317 (Glycosyl hydrolase family 99) in Endo-alpha-mannosidase. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR026071
Domain description: Glycosyl hydrolase family 99
Occurring in:
  1. Endo-alpha-mannosidase

Structure domain

CATH CATH domain
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Endo-alpha-mannosidase
The deposited structure of PDB entry 4acy contains 2 copies of CATH domain 3.20.20.80 (TIM Barrel) in Endo-alpha-mannosidase. Showing 1 copy in chain A.

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