X-ray diffraction
2.2Å resolution

Function and Biology Details

Reactions catalysed:
Acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + N-acetyl-alpha-D-glucosamine 1-phosphate
UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-alpha-D-glucosamine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Bifunctional protein GlmU Chain: A
Molecule details ›
Chain: A
Length: 459 amino acids
Theoretical weight: 49.48 KDa
Source organism: Streptococcus pneumoniae
Expression system: Escherichia coli K-12
  • Canonical: Q8DQ18 (Residues: 1-459; Coverage: 100%)
Gene names: glmU, spr0891
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P321
Unit cell:
a: 116.779Å b: 116.779Å c: 116.683Å
α: 90° β: 90° γ: 120°
R R work R free
0.202 0.2 0.237
Expression system: Escherichia coli K-12