Electron Microscopy
8.1Å resolution

Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1)


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-157723 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Actin, alpha skeletal muscle Chains: A, D, E, F, I
Molecule details ›
Chains: A, D, E, F, I
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Tropomyosin alpha-1 chain Chains: B, H
Molecule details ›
Chains: B, H
Length: 136 amino acids
Theoretical weight: 15.81 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P58772 (Residues: 98-233; Coverage: 48%)
Gene names: TPM1, TPMA
Sequence domains: Tropomyosin
Myosin IE heavy chain Chains: C, G, J
Molecule details ›
Chains: C, G, J
Length: 697 amino acids
Theoretical weight: 79.21 KDa
Source organism: Dictyostelium discoideum
Expression system: Dictyostelium discoideum
  • Canonical: Q03479 (Residues: 1-697; Coverage: 69%)
Gene names: DDB_G0288679, dmiE, myoE
Sequence domains: Myosin head (motor domain)

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 8.1Å
Relevant EMDB volumes: EMD-1989
Expression systems:
  • Escherichia coli BL21(DE3)
  • Dictyostelium discoideum