› 4a6x

X-ray diffraction
1.55Å resolution

RadA C-terminal ATPase domain from Pyrococcus furiosus bound to ATP

Released:
DOI: 10.2210/pdb4a6x/pdb
PDB 4a6x coloured by chain and viewed from the front.
PDB 4a6x coloured by chain and viewed from the side.
PDB 4a6x coloured by chain and viewed from the top.
Source organism: Pyrococcus furiosus
Entry authors: Marsh ME, Ehebauer MT, Scott D, Abell C, Blundell TL, Hyvonen M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair and recombination protein RadA Chains: A, B
Molecule details ›
Chains: A, B
Length: 231 amino acids
Theoretical weight: 25.51 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O74036 (Residues: 108-349; Coverage: 66%)
Gene names: PF1926, radA
Sequence domains: Rad51
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand ATP 2 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 40.32Å b: 87.35Å c: 61.88Å
α: 90° β: 91.23° γ: 90°
R-values:
R R work R free
0.198 0.196 0.235
Expression system: Escherichia coli BL21

Quick links

Citations

1 citations in other articles

Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
Moschetti et al. (2016)

2 mentions without citation

LS-align: an atom-level, flexible ligand structural alignment algorithm for high-throughput virtual screening.
Hu et al. (2018)
1 more