PDBe 4zig

X-ray diffraction
2.2Å resolution

Crystal Structure of core/latch dimer of Bax in complex with BidBH3mini

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apoptosis regulator BAX Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 18.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07812 (Residues: 1-166; Coverage: 87%)
  • Best match: Q07812-5 (Residues: 1-124)
Gene names: BAX, BCL2L4
Sequence domains: Apoptosis regulator proteins, Bcl-2 family
Structure domains: Blc2-like
BH3-interacting domain death agonist p13 Chain: B
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P55957 (Residues: 79-98; Coverage: 10%)
Gene name: BID

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P43212
Unit cell:
a: 100.12Å b: 100.12Å c: 37.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.181 0.229
Expression systems:
  • Escherichia coli
  • Not provided