› 4y0r

X-ray diffraction
2.3Å resolution

Bovine beta-lactoglobulin complex with pramocaine crystallized from ammonium sulphate (BLG-PRM2)

Released:
DOI: 10.2210/pdb4y0r/pdb
PDB 4y0r coloured by chain and viewed from the front.
PDB 4y0r coloured by chain and viewed from the side.
PDB 4y0r coloured by chain and viewed from the top.
Source organism: Bos taurus
Primary publication:
β-Lactoglobulin interactions with local anaesthetic drugs - Crystallographic and calorimetric studies.
Loch JI, Bonarek P, Polit A, Jabłoński M, Czub M, Ye X, Lewiński K
Int. J. Biol. Macromol. (2015)
PMID: 26092174

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactoglobulin Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.3 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02754 (Residues: 17-178; Coverage: 100%)
Gene name: LGB
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand PX9 1 x PX9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P3221
Unit cell:
a: 53.735Å b: 53.735Å c: 110.738Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.212 0.285

Quick links

Citations

1 citations in other articles

Molecular interaction of tea catechin with bovine β-lactoglobulin: A spectroscopic and in silico studies.
Al-Shabib et al. (2020)