4xtb

X-ray diffraction
1.5Å resolution

Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium uniporter protein, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NE86 (Residues: 75-185; Coverage: 32%)
Gene names: C10orf42, CCDC109A, MCU

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P65
Unit cell:
a: 55.463Å b: 55.463Å c: 68.929Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.142 0.14 0.176
Expression system: Escherichia coli