PDBe 4xlw

X-ray diffraction
3.39Å resolution

Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neurogenic locus notch homolog protein 1 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 124 amino acids
Theoretical weight: 13.52 KDa
Source organism: Rattus norvegicus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q07008 (Residues: 412-526; Coverage: 5%)
Gene name: Notch1
Sequence domains:
Structure domains: Laminin
Delta-like protein 4 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 261 amino acids
Theoretical weight: 29.15 KDa
Source organism: Rattus norvegicus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: D3ZHH1 (Residues: 28-284; Coverage: 39%)
Gene name: Dll4
Sequence domains:

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P21
Unit cell:
a: 84.56Å b: 95.57Å c: 122.9Å
α: 90° β: 96.21° γ: 90°
R-values:
R R work R free
0.26 0.257 0.31
Expression system: Trichoplusia ni