Function and Biology Details
Reaction catalysed:
ATP + H(2)O + Na(+)(Side 1) + K(+)(Side 2) = ADP + phosphate + Na(+)(Side 2) + K(+)(Side 1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Sodium/potassium-transporting ATPase subunit beta
- P-type ATPase, cytoplasmic domain N
- P-type ATPase
- Cation-transporting P-type ATPase, N-terminal
- P-type ATPase subfamily IIC, subunit alpha
- Ion-transport regulator, FXYD motif
- Ion-transport regulator, FXYD family
- Sodium/potassium-transporting ATPase subunit gamma
8 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Sodium/potassium-transporting ATPase (preferred)
PDBe Complex ID:
PDB-CPX-124366 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Sodium/potassium-transporting ATPase subunit alpha-1
Molecule details ›
Chain: A
Length: 1021 amino acids
Theoretical weight: 112.82 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 1021 amino acids
Theoretical weight: 112.82 KDa
Source organism: Bos taurus
UniProt:
- Canonical:
Q08DA1 (Residues: 1-1021; Coverage: 100%)
Sequence domains:
- Cation transporter/ATPase, N-terminus
- E1-E2 ATPase
- Cation transport ATPase (P-type)
- Cation transporting ATPase, C-terminus
Sodium/potassium-transporting ATPase subunit beta
Molecule details ›
Chain: B
Length: 303 amino acids
Theoretical weight: 35.07 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: Sodium / potassium ATPase beta chain
Structure domains:
Length: 303 amino acids
Theoretical weight: 35.07 KDa
Source organism: Bos taurus
UniProt:
- Canonical: G3MWR4 (Residues: 1-303; Coverage: 100%)
Sequence domains: Sodium / potassium ATPase beta chain
Structure domains:
Sodium/potassium-transporting ATPase subunit gamma
Molecule details ›
Chain: G
Length: 58 amino acids
Theoretical weight: 6.55 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: ATP1G1/PLM/MAT8 family
Length: 58 amino acids
Theoretical weight: 6.55 KDa
Source organism: Bos taurus
UniProt:
- Canonical: Q04645 (Residues: 1-58; Coverage: 100%)
Sequence domains: ATP1G1/PLM/MAT8 family
