4x99

X-ray diffraction
2.5Å resolution

Immunoglobulin Fc heterodimers variant

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin heavy constant gamma 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 25.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 108-330; Coverage: 68%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Immunoglobulin heavy constant gamma 1 Chain: B
Molecule details ›
Chain: B
Length: 223 amino acids
Theoretical weight: 25.08 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 108-330; Coverage: 68%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P6122
Unit cell:
a: 152.766Å b: 152.766Å c: 109.981Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.248 0.283
Expression system: Homo sapiens