PDBe 4x91

X-ray diffraction
2.3Å resolution

Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Group XV phospholipase A2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 380 amino acids
Theoretical weight: 43.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8NCC3 (Residues: 34-412; Coverage: 100%)
Gene names: LYPLA3, PLA2G15, UNQ341/PRO540
Sequence domains: Lecithin:cholesterol acyltransferase
Structure domains: Rossmann fold

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P1
Unit cell:
a: 62.83Å b: 90.172Å c: 99.345Å
α: 79.08° β: 88.88° γ: 89.11°
R-values:
R R work R free
0.181 0.179 0.212
Expression system: Homo sapiens