PDBe 4wv9

X-ray diffraction
2Å resolution

Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with click chemistry compound (3-exo)-8,8-dimethyl-3-[4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl]-8-azoniabicyclo[3.2.1]octane

Released:
Source organism: Aplysia californica
Entry authors: Talley TT, Bobango J, Wu JM, Sankaran B

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble acetylcholine receptor Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 216 amino acids
Theoretical weight: 24.57 KDa
Source organism: Aplysia californica
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WSF8 (Residues: 18-224; Coverage: 95%)
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 87.014Å b: 115.391Å c: 130.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.22
Expression system: Homo sapiens