4wet

X-ray diffraction
1.63Å resolution

Crystal structure of E.Coli DsbA in complex with compound 16

Released:

Function and Biology Details

Reaction catalysed:
2 glutathione + protein-disulfide = glutathione disulfide + protein-dithiol
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thiol:disulfide interchange protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 21.16 KDa
Source organism: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H2UL03 (Residues: 1-189; Coverage: 100%)
Sequence domains: DSBA-like thioredoxin domain
Structure domains: Glutaredoxin

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2
Unit cell:
a: 124.477Å b: 47.118Å c: 62.588Å
α: 90° β: 96.2° γ: 90°
R-values:
R R work R free
0.178 0.177 0.208