PDBe 4v0x

X-ray diffraction
1.85Å resolution

The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-684)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 33.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P63087 (Residues: 7-300; Coverage: 91%)
Gene name: Ppp1cc
Sequence domains:
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Protein phosphatase 1 regulatory subunit 15B Chain: B
Molecule details ›
Chain: B
Length: 59 amino acids
Theoretical weight: 6.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SWA1 (Residues: 631-684; Coverage: 8%)
Gene name: PPP1R15B

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P41212
Unit cell:
a: 67.54Å b: 67.54Å c: 158.01Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.222
Expression systems:
  • Escherichia coli BL21
  • Escherichia coli