4ut3

X-ray diffraction
2.19Å resolution

X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 37.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli DH5[alpha]
UniProt:
  • Canonical: P36873 (Residues: 1-323; Coverage: 100%)
Gene name: PPP1CC
Sequence domains:
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Chain: B
Molecule details ›
Chain: B
Length: 323 amino acids
Theoretical weight: 37.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli DH5[alpha]
UniProt:
  • Canonical: P36873 (Residues: 1-323; Coverage: 100%)
Gene name: PPP1CC
Sequence domains:
Structure domains: Purple Acid Phosphatase; chain A, domain 2

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 38.45Å b: 105.22Å c: 89.82Å
α: 90° β: 90.34° γ: 90°
R-values:
R R work R free
0.175 0.173 0.211
Expression system: Escherichia coli DH5[alpha]