PDBe 4tzo

X-ray diffraction
2.4Å resolution

Structure of C. elegans HTP-1 bound to HIM-3 closure motif

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Him-Three Paralog Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 253 amino acids
Theoretical weight: 28.74 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q20305 (Residues: 1-253; Coverage: 72%)
Gene names: CELE_F41H10.10, F41H10.10, htp-1
Sequence domains: HORMA domain
Structure domains: HORMA domain
High Incidence of Males (Increased X chromosome loss) Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 20 amino acids
Theoretical weight: 2.18 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: G5EBG0 (Residues: 275-291; Coverage: 6%)
Gene names: CELE_ZK381.1, ZK381.1, him-3

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 66.897Å b: 107.873Å c: 82.968Å
α: 90° β: 90.1° γ: 90°
R-values:
R R work R free
0.248 0.246 0.282
Expression system: Escherichia coli