PDBe 4tzl

X-ray diffraction
2.54Å resolution

Structure of C. elegans HTP-2 bound to HIM-3 closure motif, P21 form

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Him-Three Paralog Chains: A, B
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 28.74 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q95XC8 (Residues: 1-253; Coverage: 72%)
Gene names: CELE_Y73B6BL.2, Y73B6BL.2, htp-2
Sequence domains: HORMA domain
Structure domains: HORMA domain
High Incidence of Males (Increased X chromosome loss) Chains: C, D
Molecule details ›
Chains: C, D
Length: 20 amino acids
Theoretical weight: 2.18 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: G5EBG0 (Residues: 274-291; Coverage: 6%)
Gene names: CELE_ZK381.1, ZK381.1, him-3

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 46.745Å b: 65.685Å c: 93.685Å
α: 90° β: 90.7° γ: 90°
R-values:
R R work R free
0.198 0.196 0.23
Expression system: Escherichia coli