PDBe 4tva

X-ray diffraction
2.6Å resolution

Universal Pathway for Post-Transfer Editing Reactions: Insight from Crystal structure of TthPheRS with Puromycine


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phenylalanine--tRNA ligase alpha subunit Chain: A
Molecule details ›
Chain: A
Length: 350 amino acids
Theoretical weight: 39.31 KDa
Source organism: Thermus thermophilus
  • Canonical: P27001 (Residues: 1-350; Coverage: 100%)
Gene name: pheS
Sequence domains:
Structure domains: Bira Bifunctional Protein; Domain 2

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3221
Unit cell:
a: 173.475Å b: 173.475Å c: 138.492Å
α: 90° β: 90° γ: 120°
R R work R free
0.249 0.249 0.258