4rqi

X-ray diffraction
2.44Å resolution

Structure of TRF2/RAP1 secondary interaction binding site

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Telomeric repeat-binding factor 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 203 amino acids
Theoretical weight: 23.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: Q15554 (Residues: 85-287)
Gene names: TERF2, TRBF2, TRF2
Telomeric repeat-binding factor 2-interacting protein 1 Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 18 amino acids
Theoretical weight: 2.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Best match: Q9NYB0 (Residues: 89-106)
Gene names: DRIP5, PP8000, RAP1, TERF2IP

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21
Unit cell:
a: 53.79Å b: 104.85Å c: 85.31Å
α: 90° β: 94.39° γ: 90°
R-values:
R R work R free
0.2 0.197 0.241
Expression systems:
  • Escherichia coli
  • Not provided