Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Paxillin and Protein-tyrosine kinase 2-beta (preferred)
PDBe Complex ID:
PDB-CPX-155843 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein-tyrosine kinase 2-beta
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Focal adhesion targeting region
Structure domains: Nucleotidyltransferases domain 2
Length: 139 amino acids
Theoretical weight: 15.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q14289 (Residues: 871-1005; Coverage: 13%)
Sequence domains: Focal adhesion targeting region
Structure domains: Nucleotidyltransferases domain 2
Paxillin
Molecule details ›
Chains: B, C
Length: 24 amino acids
Theoretical weight: 2.58 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
Length: 24 amino acids
Theoretical weight: 2.58 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
- Canonical: P49024 (Residues: 139-162; Coverage: 4%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 22-ID
Spacegroup:
P6222
Expression systems:
- Escherichia coli
- Not provided
