4r1i

X-ray diffraction
3.96Å resolution

Structure and Function of Neisseria gonorrhoeae MtrF Illuminates a Class of Antimetabolite Efflux Pumps

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative efflux pump component MtrF Chains: A, B
Molecule details ›
Chains: A, B
Length: 522 amino acids
Theoretical weight: 56.17 KDa
Source organism: Neisseria gonorrhoeae FA19
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9RNX2 (Residues: 1-522; Coverage: 100%)
Gene name: mtrF
Sequence domains: AbgT putative transporter family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P65
Unit cell:
a: 120.766Å b: 120.766Å c: 233.897Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.312 0.311 0.338
Expression system: Escherichia coli