X-ray diffraction
1.53Å resolution

Crystal structure of Bcl-xL in complex with BIM BH3 domain


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 169 amino acids
Theoretical weight: 19.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q07817 (Residues: 1-209; Coverage: 73%)
Gene names: BCL2L, BCL2L1, BCLX
Sequence domains:
Bcl-2-like protein 11 Chain: B
Molecule details ›
Chain: B
Length: 26 amino acids
Theoretical weight: 3.27 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: O43521 (Residues: 141-166; Coverage: 13%)
Gene names: BCL2L11, BIM

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: C2
Unit cell:
a: 107.54Å b: 47.95Å c: 34.18Å
α: 90° β: 105.03° γ: 90°
R R work R free
0.167 0.164 0.23
Expression systems:
  • Escherichia coli
  • Not provided