PDBe 4qve

X-ray diffraction
2.05Å resolution

Crystal structure of Bcl-xL in complex with BID BH3 domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 169 amino acids
Theoretical weight: 19.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07817 (Residues: 1-209; Coverage: 73%)
Gene names: BCL2L, BCL2L1, BCLX
Sequence domains:
BH3-interacting domain death agonist p11 Chain: B
Molecule details ›
Chain: B
Length: 34 amino acids
Theoretical weight: 3.69 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P55957 (Residues: 76-109; Coverage: 17%)
Gene name: BID

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P6122
Unit cell:
a: 63.76Å b: 63.76Å c: 187.652Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.179 0.224
Expression systems:
  • Escherichia coli
  • Not provided