PDBe 4pyw

X-ray diffraction
1.91Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-1-antitrypsin Chain: A
Molecule details ›
Chain: A
Length: 404 amino acids
Theoretical weight: 45.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01009 (Residues: 26-418; Coverage: 100%)
Gene names: AAT, PI, PRO0684, PRO2209, SERPINA1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
ACE-THR-THR-ALA-ILE-NH2 Chains: B, C
Molecule details ›
Chains: B, C
Length: 6 amino acids
Theoretical weight: 429 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2
Unit cell:
a: 113.71Å b: 38.96Å c: 93.13Å
α: 90° β: 100.13° γ: 90°
R-values:
R R work R free
0.192 0.19 0.225
Expression systems:
  • Escherichia coli
  • Not provided