PDBe 4pyu

X-ray diffraction
2Å resolution

The conserved ubiquitin-like protein hub1 plays a critical role in splicing in human cells

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin-like protein 5 Chains: A, B, G, K, O, S
Molecule details ›
Chains: A, B, G, K, O, S
Length: 76 amino acids
Theoretical weight: 8.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BZL1 (Residues: 1-73; Coverage: 100%)
Gene name: UBL5
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
U4/U6.U5 tri-snRNP-associated protein 1 Chains: C, D, H, L, P, T
Molecule details ›
Chains: C, D, H, L, P, T
Length: 19 amino acids
Theoretical weight: 2.11 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43290 (Residues: 117-135; Coverage: 2%)
Gene name: SART1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 87.51Å b: 103.63Å c: 67Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.246
Expression systems:
  • Escherichia coli
  • Not provided