X-ray diffraction
2.1Å resolution

Structure of Human Polyomavirus 9 VP1 pentamer in complex with N-glycolylneuraminic acid containing 3'-sialyllactosamine


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Capsid protein VP1 Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 278 amino acids
Theoretical weight: 30.16 KDa
Source organism: Human polyomavirus 9
Expression system: Escherichia coli BL21(DE3)
  • Canonical: E9NQ90 (Residues: 32-305; Coverage: 74%)
Sequence domains: Polyomavirus coat protein
Structure domains: Capsid protein VP1,Polyomavirus

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, NGC
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 103.4Å b: 177.65Å c: 198.65Å
α: 90° β: 90° γ: 90°
R R work R free
0.186 0.184 0.224
Expression system: Escherichia coli BL21(DE3)