4pln

X-ray diffraction
3.2Å resolution

Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161331 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Netrin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 432 amino acids
Theoretical weight: 48.55 KDa
Source organism: Gallus gallus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q90922 (Residues: 26-457; Coverage: 74%)
Gene name: NTN1
Sequence domains:
Structure domains: Galactose-binding domain-like
Neogenin Chains: C, D
Molecule details ›
Chains: C, D
Length: 205 amino acids
Theoretical weight: 22.76 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P97798 (Residues: 765-980; Coverage: 14%)
Gene names: Neo1, Ngn
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 79.07Å b: 130.211Å c: 126.037Å
α: 90° β: 99.98° γ: 90°
R-values:
R R work R free
0.198 0.196 0.24
Expression system: Homo sapiens