Function and Biology Details
Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158392 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease pancreatic
Molecule details ›
Chains: A, C
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P61823 (Residues: 27-150; Coverage: 100%)
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain
Ribonuclease inhibitor
Molecule details ›
Chains: B, D
Length: 456 amino acids
Theoretical weight: 48.89 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Ribonuclease Inhibitor
Length: 456 amino acids
Theoretical weight: 48.89 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q3SZN8 (Residues: 1-456; Coverage: 100%)
Sequence domains:
Structure domains: Ribonuclease Inhibitor
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 21-ID-G
Spacegroup:
I222
Expression system: Escherichia coli BL21(DE3)
