› 4pbd

X-ray diffraction
1.68Å resolution

Crystal structure of the N-terminal CS domain of human Shq1

Released:
DOI: 10.2210/pdb4pbd/pdb
PDB entry 4pbd coloured by chain, front view.
PDB entry 4pbd coloured by chain, side view.
PDB entry 4pbd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.
Singh M, Wang Z, Cascio D, Feigon J
J Mol Biol 427 807-823 (2015)
PMID: 25553844

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180163 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein SHQ1 homolog Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6PI26 (Residues: 1-96; Coverage: 17%)
Gene name: SHQ1
Sequence domains: SHQ1-like, CS domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 41.61Å b: 41.61Å c: 132.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.204 0.243
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Assembly and trafficking of box C/D and H/ACA snoRNPs.
Massenet et al. (2017)
2 more

2 mentions without citation

Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.
Singh et al. (2015)
1 more