› 4oxf

X-ray diffraction
1.5Å resolution

Structure of ECP in complex with citrate ions at 1.50 Angstroms

Released:
DOI: 10.2210/pdb4oxf/pdb
PDB entry 4oxf coloured by chain, front view.
PDB entry 4oxf coloured by chain, side view.
PDB entry 4oxf coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Blanco JA, Boix E, Moussaoui M, Salazar VA

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146306 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eosinophil cationic protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 134 amino acids
Theoretical weight: 15.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12724 (Residues: 28-160; Coverage: 100%)
Gene names: ECP, RNASE3, RNS3
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:
Ligand CIT 5 x CIT
Ligand FE 2 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P4322
Unit cell:
a: 62.535Å b: 62.535Å c: 175.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.231
Expression system: Escherichia coli BL21(DE3)

Quick links