PDBe 4ons

X-ray diffraction
2.8Å resolution

Structural and thermodynamic characterization of cadherin-beta-catenin-alpha-catenin complex formation

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin alpha-2 Chains: A, C
Molecule details ›
Chains: A, C
Length: 248 amino acids
Theoretical weight: 27.35 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q61301 (Residues: 18-264; Coverage: 26%)
Gene names: Catna2, Ctnna2
Structure domains: Alpha-catenin/vinculin-like
Catenin beta-1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 88 amino acids
Theoretical weight: 9.91 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02248 (Residues: 78-151; Coverage: 10%)
Gene names: Catnb, Ctnnb1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P31
Unit cell:
a: 96.125Å b: 96.125Å c: 65.517Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.203 0.264
Expression system: Escherichia coli