4oee

X-ray diffraction
1.5Å resolution

Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 2 Chain: A
Molecule details ›
Chain: A
Length: 155 amino acids
Theoretical weight: 17.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P09038 (Residues: 134-288; Coverage: 54%)
Gene names: FGF2, FGFB
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL15A1
Spacegroup: C2
Unit cell:
a: 84.441Å b: 58.136Å c: 32.395Å
α: 90° β: 109.1° γ: 90°
R-values:
R R work R free
0.165 0.163 0.185
Expression system: Escherichia coli BL21