4n6p

X-ray diffraction
1.4Å resolution

Crystal Structure of C-lobe of Bovine lactoferrin complexed with meclofenamic acid at 1.4 A resolution

Released:
Source organism: Bos taurus
Entry authors: Gautam L, Dube D, Sinha M, Kaur P, Sharma S, Singh TP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 341 amino acids
Theoretical weight: 37.26 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P24627 (Residues: 361-695; Coverage: 49%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II
Lactotransferrin Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 653 Da
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P24627 (Residues: 700-705; Coverage: 1%)
Gene name: LTF

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 62.144Å b: 49.884Å c: 65.21Å
α: 90° β: 106.83° γ: 90°
R-values:
R R work R free
0.179 0.177 0.208
Expression system: Escherichia coli