4n2x

X-ray diffraction
1.7Å resolution

Crystal Structure of DL-2-haloacid dehalogenase

Released:

Function and Biology Details

Reaction catalysed:
(R)-2-haloacid + H(2)O = (S)-2-hydroxyacid + halide
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DL-2-haloacid dehalogenase Chains: A, B, D, E, F, G
Molecule details ›
Chains: A, B, D, E, F, G
Length: 301 amino acids
Theoretical weight: 34.07 KDa
Source organism: Methylobacterium sp. CPA1
Expression system: Escherichia coli
UniProt:
  • Canonical: A6BM74 (Residues: 1-301; Coverage: 100%)
Gene name: dl-dex

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P63
Unit cell:
a: 182.568Å b: 182.568Å c: 112.015Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.139 0.135 0.172
Expression system: Escherichia coli