PDBe 4mjh

X-ray diffraction
2.6Å resolution

Human Hsp27 core domain in complex with C-terminal peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Heat shock protein beta-1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 93 amino acids
Theoretical weight: 10.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04792 (Residues: 84-176; Coverage: 45%)
Gene names: HSP27, HSP28, HSPB1
Structure domains: Immunoglobulin-like
Heat shock protein beta-1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 8 amino acids
Theoretical weight: 919 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04792 (Residues: 179-186; Coverage: 4%)
Gene names: HSP27, HSP28, HSPB1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ DW
Spacegroup: P21
Unit cell:
a: 31.28Å b: 48.96Å c: 57.54Å
α: 90° β: 99.95° γ: 90°
R-values:
R R work R free
0.236 0.234 0.266
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided