4lzx

X-ray diffraction
1.5Å resolution

Complex of IQCG and Ca2+-free CaM

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-2 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP24 (Residues: 2-149; Coverage: 99%)
Gene names: CALM2, CAM2, CAMB
Sequence domains: EF-hand domain pair
Dynein regulatory complex protein 9 Chain: B
Molecule details ›
Chain: B
Length: 40 amino acids
Theoretical weight: 4.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H095 (Residues: 389-423; Coverage: 8%)
Gene names: DRC9, IQCG
Sequence domains: IQ calmodulin-binding motif

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 44.577Å b: 60.922Å c: 64.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.153 0.187
Expression system: Escherichia coli