X-ray diffraction
1.95Å resolution

Crystal structure of RNA splicing effector Prp5 in complex with ADP


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Pre-mRNA-processing ATP-dependent RNA helicase PRP5 Chain: A
Molecule details ›
Chain: A
Length: 493 amino acids
Theoretical weight: 55.72 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
  • Canonical: P21372 (Residues: 206-698; Coverage: 58%)
Gene names: PRP5, RNA5, YBR1603, YBR237W
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43212
Unit cell:
a: 86.598Å b: 86.598Å c: 125.316Å
α: 90° β: 90° γ: 90°
R R work R free
0.202 0.201 0.226
Expression system: Escherichia coli